Ford and Joseph will line-up at fly-half and outside centre respectively, as England look to make it two wins out of two following their 19-16 opening weekend victory over France.

There are two changes to the starting XV with Exerter Chiefs' Jack Nowell (Exeter Chiefs) starting on the right wing and Harlequin's Jack Clifford named at flanker to win his ninth cap.

Tom Wood (Northampton Saints) and Jonny May (Gloucester Rugby) are included as finishers in an otherwise unchanged bench.

“It’s been a great week of focused preparation and we can’t wait to play Wales,” said England head coach Eddie Jones.

“Playing Wales in Cardiff is one of the biggest games in world rugby and we’re excited. These are the games you want to be part of as a player and a coach.

“It’s a game that is going to be decided on the basics of the game. You do the fundamentals of the game well and you win the game of rugby. We have a young team eager to play well at the great Principality Stadium.

“Jack Nowell starts this week with Jonny May changing to a finisher. Jack has an excellent work-rate and he’s a guy that carries through the line which will be important for us.

“Jack Clifford also deserves his starting role. He is a hard-working, young player. He has got a good record against Wales, he had a superb game against them in May, he knows what he is going to expect from Wales and we’re looking forward to him making an impact to our back-row play. Tom Wood will also play his part later in the game off the bench as a finisher.

“We don’t need extra motivation this week; we play Test rugby because we want to be the best for England. Every game for us is important and our supporters, and Wales is our next game so it’s the most important.”

England team to face Wales

15. Mike Brown (vice captain, Harlequins, 56 caps)
14. Jack Nowell (Exeter Chiefs, 19 caps)
13. Jonathan Joseph (Bath Rugby, 30 caps)
12. Owen Farrell (vice captain, Saracens, 48 caps)
11. Elliot Daly (Wasps, 9 caps)
10. George Ford (Bath Rugby, 31 caps)
9. Ben Youngs (Leicester Tigers, 66 caps)
1. Joe Marler (Harlequins, 47 caps)
2. Dylan Hartley (captain, Northampton Saints, 80 caps)
3. Dan Cole (Leicester Tigers, 70 caps)
4. Joe Launchbury (Wasps, 38 caps)
5. Courtney Lawes (Northampton Saints, 54 caps)
6. Maro Itoje (Saracens, 8 caps)
7. Jack Clifford (Harlequins, 8 caps)
8. Nathan Hughes (Wasps, 4 caps)

Replacements

16. Jamie George (Saracens, 13 caps)
17. Matt Mullan (Wasps, 14 caps)
18. Kyle Sinckler (Harlequins, 4 caps)
19. Tom Wood (Northampton Saints, 46 caps)
20. James Haskell (Wasps, 71 caps)
21. Danny Care (Harlequins, 67 caps)
22. Ben Te’o (Worcester Warriors, 4 caps)
23. Jonny May (Gloucester Rugby, 23 caps)

Bath Rugby duo start for England against Wales

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